Naturally I have strong anti-spam and antivirus defences on the domains I host. All are based on Open Source code and tech and have worked very well indeed - Postfix for the mail itself, Clam Antivirus + clamsmtpd (the latter I also package for Fedora, see my package repository above) plus Bogofilter for Bayes classification of incoming messages.
I also maintain my own domain-wide blacklist of banned addresses and domains. If you ever see a bounce from my system (currently qbert.enlartenment.com) with a:
554 Spam Blacklisted
...message, you've made my list for being a bad boy/girl. If you want to check if you're listed, the blacklist check form will let you know.
If you think it's in error, I have working postmaster and abuse role accounts at my domains that accept all mail. I'm reasonable - as long as you are also. Abusive mails will be posted for the amusement of myself and visitors.